Conformational Heterogeneity of the HIV Envelope Glycan Shield

To better understand the conformational properties of the glycan shield covering the surface of the HIV gp120/gp41 envelope (Env) trimer, and how the glycan shield impacts the accessibility of the underlying protein surface, we performed enhanced sampling molecular dynamics (MD) simulations of a mod...

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Detalles Bibliográficos
Autores principales: Yang, Mingjun, Huang, Jing, Simon, Raphael, Wang, Lai-Xi, MacKerell, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493700/
https://www.ncbi.nlm.nih.gov/pubmed/28667249
http://dx.doi.org/10.1038/s41598-017-04532-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493700/
https://www.ncbi.nlm.nih.gov/pubmed/28667249
http://dx.doi.org/10.1038/s41598-017-04532-9

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