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The Hippo pathway acts downstream of the Hedgehog signaling to regulate follicle stem cell maintenance in the Drosophila ovary
The Hippo pathway is conserved and plays important roles in organ size control. The core components of the Hippo pathway are two kinases Hippo (Hpo), Warts (Wts), and a transcription-co-activator Yorkie (Yki). Yki activity is regulated by phosphorylation, which affects its nuclear localization and s...
Autores principales: | Hsu, Ta-Hsing, Yang, Chia-Yu, Yeh, Tsung-Han, Huang, Yi-Chia, Wang, Tsu-Wei, Yu, Jenn-Yah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493701/ https://www.ncbi.nlm.nih.gov/pubmed/28667262 http://dx.doi.org/10.1038/s41598-017-04052-6 |
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