SUMOylation pathway alteration coupled with downregulation of SUMO E2 enzyme at mucosal epithelium modulates inflammation in inflammatory bowel disease

Post-translational modification pathways such as SUMOylation are integral to all cellular processes and tissue homeostasis. We investigated the possible involvement of SUMOylation in the epithelial signalling in Crohn's disease (CD) and ulcerative colitis (UC), the two major forms of inflammato...

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Detalles Bibliográficos
Autores principales: Mustfa, Salman Ahmad, Singh, Mukesh, Suhail, Aamir, Mohapatra, Gayatree, Verma, Smriti, Chakravorty, Debangana, Rana, Sarika, Rampal, Ritika, Dhar, Atika, Saha, Sudipto, Ahuja, Vineet, Srikanth, C. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493774/
https://www.ncbi.nlm.nih.gov/pubmed/28659381
http://dx.doi.org/10.1098/rsob.170024

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