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Recognition of a glycosylation substrate by the O-GlcNAc transferase TPR repeats
O-linked N-acetylglucosamine (O-GlcNAc) is an essential and dynamic post-translational modification found on hundreds of nucleocytoplasmic proteins in metazoa. Although a single enzyme, O-GlcNAc transferase (OGT), generates the entire cytosolic O-GlcNAc proteome, it is not understood how it recogniz...
Autores principales: | Rafie, Karim, Raimi, Olawale, Ferenbach, Andrew T., Borodkin, Vladimir S., Kapuria, Vaibhav, van Aalten, Daan M. F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493779/ https://www.ncbi.nlm.nih.gov/pubmed/28659383 http://dx.doi.org/10.1098/rsob.170078 |
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