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A Bayesian approach to estimating hidden variables as well as missing and wrong molecular interactions in ordinary differential equation-based mathematical models

Ordinary differential equations (ODEs) are a popular approach to quantitatively model molecular networks based on biological knowledge. However, such knowledge is typically restricted. Wrongly modelled biological mechanisms as well as relevant external influence factors that are not included into th...

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Detalles Bibliográficos
Autores principales: Engelhardt, Benjamin, Kschischo, Maik, Fröhlich, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493809/
https://www.ncbi.nlm.nih.gov/pubmed/28615495
http://dx.doi.org/10.1098/rsif.2017.0332