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Genetic diversity and natural selection of Plasmodium vivax multi-drug resistant gene (pvmdr1) in Mesoamerica

BACKGROUND: The Plasmodium vivax multidrug resistant 1 gene (pvmdr1) codes for a transmembrane protein of the parasite’s digestive vacuole. It is likely that the pvmdr1 gene mutations occur at different sites by convergent evolution. In here, the genetic variation of pvmdr1 at three sites of the Mes...

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Detalles Bibliográficos
Autores principales: González-Cerón, Lilia, Montoya, Alberto, Corzo-Gómez, Josselin C., Cerritos, Rene, Santillán, Frida, Sandoval, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493867/
https://www.ncbi.nlm.nih.gov/pubmed/28666481
http://dx.doi.org/10.1186/s12936-017-1905-x

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