Combination of t(4;14), del(17p13), del(1p32) and 1q21 gain FISH probes identifies clonal heterogeneity and enhances the detection of adverse cytogenetic profiles in 233 newly diagnosed multiple myeloma

BACKGROUND: Our aim was to set the FISH combination of del(17p13), t(4;14), 1q21 gain and del(1p32), four adverse cytogenetic factors rarely evaluated together, and compare our technical thresholds with those defined in the literature. METHODS: Two hundred thirty-three patients with MM at diagnosis...

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Detalles Bibliográficos
Autores principales: Smol, Thomas, Dufour, Annika, Tricot, Sabine, Wemeau, Mathieu, Stalnikiewicz, Laure, Bernardi, Franck, Terré, Christine, Ducourneau, Benoît, Bisiau, Hervé, Daudignon, Agnès
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493886/
https://www.ncbi.nlm.nih.gov/pubmed/28680482
http://dx.doi.org/10.1186/s13039-017-0327-3

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