Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users

Sixty-one percent of intravenous drug users (IVDUs) who received outpatient parenteral antibiotic therapy (OPAT) failed treatment. Hospital readmission and adverse drug reactions occurred in 25%. By multivariate analysis, time since last IVDU was associated with failure (P = .04). Intravenous drug u...

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Autores principales: Buehrle, Deanna J., Shields, Ryan K., Shah, Neel, Shoff, Christopher, Sheridan, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493937/
https://www.ncbi.nlm.nih.gov/pubmed/28680904
http://dx.doi.org/10.1093/ofid/ofx102
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author Buehrle, Deanna J.
Shields, Ryan K.
Shah, Neel
Shoff, Christopher
Sheridan, Kathleen
author_facet Buehrle, Deanna J.
Shields, Ryan K.
Shah, Neel
Shoff, Christopher
Sheridan, Kathleen
author_sort Buehrle, Deanna J.
collection PubMed
description Sixty-one percent of intravenous drug users (IVDUs) who received outpatient parenteral antibiotic therapy (OPAT) failed treatment. Hospital readmission and adverse drug reactions occurred in 25%. By multivariate analysis, time since last IVDU was associated with failure (P = .04). Intravenous drug users requiring OPAT are at high risk for failure; additional studies are needed to explore alternatives.
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spelling pubmed-54939372017-07-05 Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users Buehrle, Deanna J. Shields, Ryan K. Shah, Neel Shoff, Christopher Sheridan, Kathleen Open Forum Infect Dis Brief Report Sixty-one percent of intravenous drug users (IVDUs) who received outpatient parenteral antibiotic therapy (OPAT) failed treatment. Hospital readmission and adverse drug reactions occurred in 25%. By multivariate analysis, time since last IVDU was associated with failure (P = .04). Intravenous drug users requiring OPAT are at high risk for failure; additional studies are needed to explore alternatives. Oxford University Press 2017-05-23 /pmc/articles/PMC5493937/ /pubmed/28680904 http://dx.doi.org/10.1093/ofid/ofx102 Text en © The Author 2017. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Brief Report
Buehrle, Deanna J.
Shields, Ryan K.
Shah, Neel
Shoff, Christopher
Sheridan, Kathleen
Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users
title Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users
title_full Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users
title_fullStr Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users
title_full_unstemmed Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users
title_short Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users
title_sort risk factors associated with outpatient parenteral antibiotic therapy program failure among intravenous drug users
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493937/
https://www.ncbi.nlm.nih.gov/pubmed/28680904
http://dx.doi.org/10.1093/ofid/ofx102
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