Effects of Poly(ADP-Ribose) Polymerase-1 Inhibition in a Neonatal Rodent Model of Hypoxic-Ischemic Injury

BACKGROUND: Hypoxia ischemia (HI) to the developing brain occurs in 1–6 in 1000 live births. Large numbers of survivors have neurological long-term sequelae. However, mechanisms of recovery after HI are not understood and preventive measures or clinical treatments are not effective. Poly(ADP-ribose)...

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Detalles Bibliográficos
Autores principales: Klöfers, Melanie, Kohaut, Jules, Bendix, Ivo, Herz, Josephine, Boos, Vinzenz, Felderhoff-Müser, Ursula, Dzietko, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494065/
https://www.ncbi.nlm.nih.gov/pubmed/28698869
http://dx.doi.org/10.1155/2017/2924848

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