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HIV-1 integrase crosslinked oligomers are active in vitro

The oligomeric state of active human immunodeficiency virus type 1 (HIV-1) integrase (IN) has not been clearly elucidated. We analyzed the activity of the different purified oligomeric forms of recombinant IN obtained after stabilization by platinum crosslinking. The crosslinked tetramer isolated by...

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Detalles Bibliográficos
Autores principales:	Faure, Aurélie, Calmels, Christina, Desjobert, Cécile, Castroviejo, Michel, Caumont-Sarcos, Anne, Tarrago-Litvak, Laura, Litvak, Simon, Parissi, Vincent
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549407/ https://www.ncbi.nlm.nih.gov/pubmed/15718297 http://dx.doi.org/10.1093/nar/gki241

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