Cargando…
Preclinical Studies and Translational Applications of Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) which refers to bleeding in the brain is a very deleterious condition with high mortality and disability rate. Surgery or conservative therapy remains the treatment option. Various studies have divided the disease process of ICH into primary and secondary injury, for w...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494071/ https://www.ncbi.nlm.nih.gov/pubmed/28698874 http://dx.doi.org/10.1155/2017/5135429 |
_version_ | 1783247611171438592 |
---|---|
author | Siaw-Debrah, Felix Nyanzu, Mark Ni, Haoqi Lin, Xiao Xu, Zhu Ruan, Linhui Zhuge, Qichuan Huang, Lijie |
author_facet | Siaw-Debrah, Felix Nyanzu, Mark Ni, Haoqi Lin, Xiao Xu, Zhu Ruan, Linhui Zhuge, Qichuan Huang, Lijie |
author_sort | Siaw-Debrah, Felix |
collection | PubMed |
description | Intracerebral hemorrhage (ICH) which refers to bleeding in the brain is a very deleterious condition with high mortality and disability rate. Surgery or conservative therapy remains the treatment option. Various studies have divided the disease process of ICH into primary and secondary injury, for which knowledge into these processes has yielded many preclinical and clinical treatment options. The aim of this review is to highlight some of the new experimental drugs as well as other treatment options like stem cell therapy, rehabilitation, and nanomedicine and mention some translational clinical applications that have been done with these treatment options. |
format | Online Article Text |
id | pubmed-5494071 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-54940712017-07-11 Preclinical Studies and Translational Applications of Intracerebral Hemorrhage Siaw-Debrah, Felix Nyanzu, Mark Ni, Haoqi Lin, Xiao Xu, Zhu Ruan, Linhui Zhuge, Qichuan Huang, Lijie Biomed Res Int Review Article Intracerebral hemorrhage (ICH) which refers to bleeding in the brain is a very deleterious condition with high mortality and disability rate. Surgery or conservative therapy remains the treatment option. Various studies have divided the disease process of ICH into primary and secondary injury, for which knowledge into these processes has yielded many preclinical and clinical treatment options. The aim of this review is to highlight some of the new experimental drugs as well as other treatment options like stem cell therapy, rehabilitation, and nanomedicine and mention some translational clinical applications that have been done with these treatment options. Hindawi 2017 2017-06-18 /pmc/articles/PMC5494071/ /pubmed/28698874 http://dx.doi.org/10.1155/2017/5135429 Text en Copyright © 2017 Felix Siaw-Debrah et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Siaw-Debrah, Felix Nyanzu, Mark Ni, Haoqi Lin, Xiao Xu, Zhu Ruan, Linhui Zhuge, Qichuan Huang, Lijie Preclinical Studies and Translational Applications of Intracerebral Hemorrhage |
title | Preclinical Studies and Translational Applications of Intracerebral Hemorrhage |
title_full | Preclinical Studies and Translational Applications of Intracerebral Hemorrhage |
title_fullStr | Preclinical Studies and Translational Applications of Intracerebral Hemorrhage |
title_full_unstemmed | Preclinical Studies and Translational Applications of Intracerebral Hemorrhage |
title_short | Preclinical Studies and Translational Applications of Intracerebral Hemorrhage |
title_sort | preclinical studies and translational applications of intracerebral hemorrhage |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494071/ https://www.ncbi.nlm.nih.gov/pubmed/28698874 http://dx.doi.org/10.1155/2017/5135429 |
work_keys_str_mv | AT siawdebrahfelix preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage AT nyanzumark preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage AT nihaoqi preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage AT linxiao preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage AT xuzhu preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage AT ruanlinhui preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage AT zhugeqichuan preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage AT huanglijie preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage |