Cargando…

Preclinical Studies and Translational Applications of Intracerebral Hemorrhage

Intracerebral hemorrhage (ICH) which refers to bleeding in the brain is a very deleterious condition with high mortality and disability rate. Surgery or conservative therapy remains the treatment option. Various studies have divided the disease process of ICH into primary and secondary injury, for w...

Descripción completa

Detalles Bibliográficos
Autores principales: Siaw-Debrah, Felix, Nyanzu, Mark, Ni, Haoqi, Lin, Xiao, Xu, Zhu, Ruan, Linhui, Zhuge, Qichuan, Huang, Lijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494071/
https://www.ncbi.nlm.nih.gov/pubmed/28698874
http://dx.doi.org/10.1155/2017/5135429
_version_ 1783247611171438592
author Siaw-Debrah, Felix
Nyanzu, Mark
Ni, Haoqi
Lin, Xiao
Xu, Zhu
Ruan, Linhui
Zhuge, Qichuan
Huang, Lijie
author_facet Siaw-Debrah, Felix
Nyanzu, Mark
Ni, Haoqi
Lin, Xiao
Xu, Zhu
Ruan, Linhui
Zhuge, Qichuan
Huang, Lijie
author_sort Siaw-Debrah, Felix
collection PubMed
description Intracerebral hemorrhage (ICH) which refers to bleeding in the brain is a very deleterious condition with high mortality and disability rate. Surgery or conservative therapy remains the treatment option. Various studies have divided the disease process of ICH into primary and secondary injury, for which knowledge into these processes has yielded many preclinical and clinical treatment options. The aim of this review is to highlight some of the new experimental drugs as well as other treatment options like stem cell therapy, rehabilitation, and nanomedicine and mention some translational clinical applications that have been done with these treatment options.
format Online
Article
Text
id pubmed-5494071
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-54940712017-07-11 Preclinical Studies and Translational Applications of Intracerebral Hemorrhage Siaw-Debrah, Felix Nyanzu, Mark Ni, Haoqi Lin, Xiao Xu, Zhu Ruan, Linhui Zhuge, Qichuan Huang, Lijie Biomed Res Int Review Article Intracerebral hemorrhage (ICH) which refers to bleeding in the brain is a very deleterious condition with high mortality and disability rate. Surgery or conservative therapy remains the treatment option. Various studies have divided the disease process of ICH into primary and secondary injury, for which knowledge into these processes has yielded many preclinical and clinical treatment options. The aim of this review is to highlight some of the new experimental drugs as well as other treatment options like stem cell therapy, rehabilitation, and nanomedicine and mention some translational clinical applications that have been done with these treatment options. Hindawi 2017 2017-06-18 /pmc/articles/PMC5494071/ /pubmed/28698874 http://dx.doi.org/10.1155/2017/5135429 Text en Copyright © 2017 Felix Siaw-Debrah et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Siaw-Debrah, Felix
Nyanzu, Mark
Ni, Haoqi
Lin, Xiao
Xu, Zhu
Ruan, Linhui
Zhuge, Qichuan
Huang, Lijie
Preclinical Studies and Translational Applications of Intracerebral Hemorrhage
title Preclinical Studies and Translational Applications of Intracerebral Hemorrhage
title_full Preclinical Studies and Translational Applications of Intracerebral Hemorrhage
title_fullStr Preclinical Studies and Translational Applications of Intracerebral Hemorrhage
title_full_unstemmed Preclinical Studies and Translational Applications of Intracerebral Hemorrhage
title_short Preclinical Studies and Translational Applications of Intracerebral Hemorrhage
title_sort preclinical studies and translational applications of intracerebral hemorrhage
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494071/
https://www.ncbi.nlm.nih.gov/pubmed/28698874
http://dx.doi.org/10.1155/2017/5135429
work_keys_str_mv AT siawdebrahfelix preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage
AT nyanzumark preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage
AT nihaoqi preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage
AT linxiao preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage
AT xuzhu preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage
AT ruanlinhui preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage
AT zhugeqichuan preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage
AT huanglijie preclinicalstudiesandtranslationalapplicationsofintracerebralhemorrhage