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Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer’s disease

F1FO-ATP synthase is critical for mitochondrial functions. The deregulation of this enzyme results in dampened mitochondrial oxidative phosphorylation (OXPHOS) and activated mitochondrial permeability transition (mPT), defects which accompany Alzheimer’s disease (AD). However, the molecular mechanis...

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Detalles Bibliográficos
Autores principales:	Beck, Simon J., Guo, Lan, Phensy, Aarron, Tian, Jing, Wang, Lu, Tandon, Neha, Gauba, Esha, Lu, Lin, Pascual, Juan M., Kroener, Sven, Du, Heng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494197/ https://www.ncbi.nlm.nih.gov/pubmed/27151236 http://dx.doi.org/10.1038/ncomms11483

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