Functional characterization of the mitochondrial 12S rRNA C1494T mutation associated with aminoglycoside-induced and non-syndromic hearing loss

In this study, we report the biochemical characterization of the deafness-associated mitochondrial 12S rRNA C1494T mutation using 27 cybrid cell lines constructed by transferring mitochondria from 9 lymphoblastoid cell lines derived from a Chinese family into human mitochondrial DNA (mtDNA)-less (ρ°...

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Detalles Bibliográficos
Autores principales: Zhao, Hui, Young, Wie-Yen, Yan, Qingfeng, Li, Ronghua, Cao, Juyang, Wang, Qiuju, Li, Xiaoming, Peters, Jennifer L., Han, Dongyi, Guan, Min-Xin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549421/
https://www.ncbi.nlm.nih.gov/pubmed/15722487
http://dx.doi.org/10.1093/nar/gki262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549421/
https://www.ncbi.nlm.nih.gov/pubmed/15722487
http://dx.doi.org/10.1093/nar/gki262

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