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Use of mRNA- and protein-destabilizing elements to develop a highly responsive reporter system

Reporter assays are widely used in applications that require measurement of changes in gene expression over time (e.g. drug screening). With standard reporter vectors, the measurable effect of a treatment or compound (altered reporter activity) is substantially diluted and delayed, compared with its...

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Detalles Bibliográficos
Autores principales: Voon, Dominic C., Subrata, Lily S., Baltic, Svetlana, Leu, Marco P., Whiteway, Joanna M., Wong, Agnes, Knight, Samuel A., Christiansen, Frank T., Daly, John M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549429/
https://www.ncbi.nlm.nih.gov/pubmed/15716309
http://dx.doi.org/10.1093/nar/gni030