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Use of mRNA- and protein-destabilizing elements to develop a highly responsive reporter system
Reporter assays are widely used in applications that require measurement of changes in gene expression over time (e.g. drug screening). With standard reporter vectors, the measurable effect of a treatment or compound (altered reporter activity) is substantially diluted and delayed, compared with its...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549429/ https://www.ncbi.nlm.nih.gov/pubmed/15716309 http://dx.doi.org/10.1093/nar/gni030 |