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Discovery of active proteins directly from combinatorial randomized protein libraries without display, purification or sequencing: identification of novel zinc finger proteins
We have successfully linked protein library screening directly with the identification of active proteins, without the need for individual purification, display technologies or physical linkage between the protein and its encoding sequence. By using ‘MAX’ randomization we have rapidly constructed 60...
Autores principales: | Hughes, Marcus D., Zhang, Zhan-Ren, Sutherland, Andrew J., Santos, Albert F., Hine, Anna V. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549430/ https://www.ncbi.nlm.nih.gov/pubmed/15722478 http://dx.doi.org/10.1093/nar/gni031 |
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