Cargando…

Deguelin inhibits epithelial‐to‐mesenchymal transition and metastasis of human non‐small cell lung cancer cells by regulating NIMA‐related kinase 2

BACKGROUND: Non‐small cell lung cancer is a lethal malignancy with a high mortality rate. Deguelin displays an anti‐tumor effect and inhibits metastasis in various cancers. The aberrant expression of NIMA‐related kinase 2 (NEK2) indicates poor prognosis and induces epithelial‐to‐mesenchymal transiti...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Dejian, Han, Wenzheng, Liu, Xia, Cui, Dawei, Chen, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494456/
https://www.ncbi.nlm.nih.gov/pubmed/28509438
http://dx.doi.org/10.1111/1759-7714.12444