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Deguelin inhibits epithelial‐to‐mesenchymal transition and metastasis of human non‐small cell lung cancer cells by regulating NIMA‐related kinase 2
BACKGROUND: Non‐small cell lung cancer is a lethal malignancy with a high mortality rate. Deguelin displays an anti‐tumor effect and inhibits metastasis in various cancers. The aberrant expression of NIMA‐related kinase 2 (NEK2) indicates poor prognosis and induces epithelial‐to‐mesenchymal transiti...
Autores principales: | Zhao, Dejian, Han, Wenzheng, Liu, Xia, Cui, Dawei, Chen, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Australia, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494456/ https://www.ncbi.nlm.nih.gov/pubmed/28509438 http://dx.doi.org/10.1111/1759-7714.12444 |
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