Human lactoferrin efficiently targeted into caprine beta-lactoglobulin locus with transcription activator-like effector nucleases

OBJECTIVE: To create genetically modified goat as a biopharming source of recombinant human lacotoferrin (hLF) with transcription activator-like effector nucleases. METHODS: TALENs and targeting vector were transferred into cultured fibroblasts to insert hLF cDNA in the goat beta-lactoglobulin (BLG)...

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Detalles Bibliográficos
Autores principales: Yuan, Yu-Guo, Song, Shao-Zheng, Zhu, Meng-Ming, He, Zheng-Yi, Lu, Rui, Zhang, Ting, Mi, Fei, Wang, Jin-Yu, Cheng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494492/
https://www.ncbi.nlm.nih.gov/pubmed/28002927
http://dx.doi.org/10.5713/ajas.16.0697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494492/
https://www.ncbi.nlm.nih.gov/pubmed/28002927
http://dx.doi.org/10.5713/ajas.16.0697

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