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Highly sensitive and multiplexed analysis of CpG methylation at single-base resolution with ligation-based exponential amplification
DNA methylation is a primary epigenetic mechanism for transcriptional regulation during normal development and the occurrence of diseases, including cancers. DNA methylation has been increasingly utilized as a biomarker for cancer detection and differential diagnosis. Generally, one type of cancer i...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494546/ https://www.ncbi.nlm.nih.gov/pubmed/28706642 http://dx.doi.org/10.1039/c4sc03135k |