The C-Terminal Effector Domain of Non-Structural Protein 1 of Influenza A Virus Blocks IFN-β Production by Targeting TNF Receptor-Associated Factor 3

Influenza A virus non-structural protein 1 (NS1) antagonizes interferon response through diverse strategies, particularly by inhibiting the activation of interferon regulatory factor 3 (IRF3) and IFN-β transcription. However, the underlying mechanisms used by the NS1 C-terminal effector domain (ED)...

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Detalles Bibliográficos
Autores principales: Qian, Wei, Wei, Xiaoqin, Guo, Kelei, Li, Yongtao, Lin, Xian, Zou, Zhong, Zhou, Hongbo, Jin, Meilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494602/
https://www.ncbi.nlm.nih.gov/pubmed/28717359
http://dx.doi.org/10.3389/fimmu.2017.00779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494602/
https://www.ncbi.nlm.nih.gov/pubmed/28717359
http://dx.doi.org/10.3389/fimmu.2017.00779

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