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Combination of palbociclib and radiotherapy for glioblastoma

The cyclin-dependent kinase inhibitor, palbociclib has shown compelling efficacy in breast cancer patients. Several pre-clinical studies of glioblastoma (GBM) have also shown palbociclib to be efficacious. In this study, we investigated palbociclib in combination with radiation therapy (RT) for trea...

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Detalles Bibliográficos
Autores principales: Whittaker, Shane, Madani, Daniel, Joshi, Swapna, Chung, Sylvia A, Johns, Terrance, Day, Bryan, Khasraw, Mustafa, McDonald, Kerrie L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494656/
https://www.ncbi.nlm.nih.gov/pubmed/28690875
http://dx.doi.org/10.1038/cddiscovery.2017.33