Cargando…

Involvement of the TGFβ1/Smad2/MMP3 signaling pathway in SB431542-induced inhibition of cell invasion in multiple myeloma RPMI 8226 cells

Multiple myeloma (MM) is a malignancy characterized by plasma cell hyperplasia. The majority of patients with MM suffer from mortality due to tumor recurrence and metastasis, which has become an emerging clinical problem. Transforming growth factor β1 (TGFβ1) has been implicated in tumor metastasis;...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xi, Huang, Shuai, Qi-Guo, Shao, Lin-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494695/ https://www.ncbi.nlm.nih.gov/pubmed/28693203 http://dx.doi.org/10.3892/ol.2017.6263

Ejemplares similares

The Mitochondria-Independent Cytotoxic Effect of Leflunomide on RPMI-8226 Multiple Myeloma Cell Line
por: Adamczuk, Grzegorz, et al.
Publicado: (2021)

Activation of murine 'T' lymphomas in the presence of a human myeloma cell line, RPMI-8226, in vivo.
por: Millar, B. C., et al.
Publicado: (1988)

SB431542 inhibited cigarette smoke extract induced invasiveness of A549 cells via the TGF-β1/Smad2/MMP3 pathway
por: Liao, Ke, et al.
Publicado: (2018)

Abnormal cytokine production by bone marrow stromal cells of multiple myeloma patients in response to RPMI8226 myeloma cells
por: Zdzisińska, Barbara, et al.
Publicado: (2008)

The TGF-β/Smad Pathway Inhibitor SB431542 Enhances The Antitumor Effect Of Radiofrequency Ablation On Bladder Cancer Cells
por: Zhou, Hong-qing, et al.
Publicado: (2019)

Role and Mechanism of circ_0058063/miR-635 Axis in the Malignant Phenotype of Multiple Myeloma RPMI8226 Cells
por: Li, Xiaoya, et al.
Publicado: (2021)

Habb-e-Asgandh Suppresses Cell Proliferation and Induces Apoptosis through Mitochondria Dysfunction in Multiple Myeloma Cells (RPMI8226)
por: Vashist, Annu, et al.
Publicado: (2022)

Engagement of CD99 Reduces AP-1 Activity by Inducing BATF in the Human Multiple Myeloma Cell Line RPMI8226
por: Gil, Minchan, et al.
Publicado: (2015)

Retracted: Role and Mechanism of circ_0058063/miR-635 Axis in the Malignant Phenotype of Multiple Myeloma RPMI8226 Cells
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Low dose dinaciclib enhances doxorubicin-induced senescence in myeloma RPMI8226 cells by transformation of the p21 and p16 pathways
por: Tang, Hailong, et al.
Publicado: (2018)

Human P2X7 Receptor Causes Cycle Arrest in RPMI-8226 Myeloma Cells to Alter the Interaction with Osteoblasts and Osteoclasts
por: Agrawal, Ankita, et al.
Publicado: (2020)

TGF-β Inhibitor SB431542 Promotes the Differentiation of Induced Pluripotent Stem Cells and Embryonic Stem Cells into Mesenchymal-Like Cells
por: Leyendecker Junior, Alessander
Publicado: (2018)

Construction of a recombinant lentivirus-mediated shRNA expression vector targeting the human PSMD10 gene and validation of RNAi efficiency in RPMI-8226 multiple myeloma cells
por: Du, Siyue, et al.
Publicado: (2017)

脑源性神经营养因子基因沉默对RPMI8226细胞表达VEGF的影响
Publicado: (2015)

Regulator of G Protein Signaling 1 Suppresses CXCL12-Mediated Migration and AKT Activation in RPMI 8226 Human Plasmacytoma Cells and Plasmablasts
por: Pak, Hyo-Kyung, et al.
Publicado: (2015)

Force-Regulated Calcium Signaling of Lymphoid Cell RPMI 8226 Mediated by Integrin α(4)β(7)/MAdCAM-1 in Flow
por: Sun, Dongshan, et al.
Publicado: (2023)

Radiosensitization of Non-Small Cell Lung Cancer Cells by Inhibition of TGF-β1 Signaling With SB431542 Is Dependent on p53 Status
por: Zhao, Yifan, et al.
Publicado: (2016)

Dual Inhibition of Activin/Nodal/TGF-β and BMP Signaling Pathways by SB431542 and Dorsomorphin Induces Neuronal Differentiation of Human Adipose Derived Stem Cells
por: Madhu, Vedavathi, et al.
Publicado: (2016)

Inducing cell cycle arrest and apoptosis by dimercaptosuccinic acid modified Fe(3)O(4) magnetic nanoparticles combined with nontoxic concentration of bortezomib and gambogic acid in RPMI-8226 cells
por: Zhang, Wei, et al.
Publicado: (2015)

TGF-β Small Molecule Inhibitor SB431542 Reduces Rotator Cuff Muscle Fibrosis and Fatty Infiltration By Promoting Fibro/Adipogenic Progenitor Apoptosis
por: Davies, Michael R., et al.
Publicado: (2016)

Combination of SB431542, Chir9901, and Bpv as a novel supplement in the culture of umbilical cord blood hematopoietic stem cells
por: Zarrabi, Morteza, et al.
Publicado: (2020)

CPT联合美法仑对人多发性骨髓瘤细胞株RPMI8226细胞增殖的影响及其机制
Publicado: (2019)

丙戊酸钠对多发性骨髓瘤细胞株RPMI8226和U266细胞自噬的影响
Publicado: (2016)

泊马度胺联合CAR-T细胞对多发性骨髓瘤细胞株RPMI8226、U266细胞的体外杀伤作用
Publicado: (2015)

靶向抑制miR155表达对耐阿霉素多发性骨髓瘤细胞株RPMI8226/DOX耐药性的影响
Publicado: (2017)

ALK5 Inhibition of Subconjunctival Scarring From Glaucoma Surgery: Effects of SB-431542 Compared to Mitomycin C in Human Tenon's Capsule Fibroblasts
por: Teplitsky, Jack E., et al.
Publicado: (2023)

Secondary Analysis of the NCI-60 Whole Exome Sequencing Data Indicates Significant Presence of Propionibacterium acnes Genomic Material in Leukemia (RPMI-8226) and Central Nervous System (SF-295, SF-539, and SNB-19) Cell Lines
por: Rojas, Mark, et al.
Publicado: (2015)

HaCaT-conditioned medium supplemented with the small molecule inhibitors SB431542 and CHIR99021 and the growth factor PDGF-AA prevents the dedifferentiation of dermal papilla cells in vitro
por: Sun, Dongjie, et al.
Publicado: (2021)

Inhibition of tumor invasion and metastasis by targeting TGF-β-Smad-MMP2 pathway with Asiatic acid and Naringenin
por: Lian, Guang-Yu, et al.
Publicado: (2021)

Cytotoxicity of Different Excipients on RPMI 2650 Human Nasal Epithelial Cells
por: Horváth, Tamás, et al.
Publicado: (2016)

Genetic heterogeneity of RPMI-8402, a T-acute lymphoblastic leukemia cell line
por: STOCZYNSKA-FIDELUS, EWELINA, et al.
Publicado: (2016)

Applicability of RPMI 2650 and Calu-3 Cell Models for Evaluation of Nasal Formulations
por: Sibinovska, Nadica, et al.
Publicado: (2022)

TGF-β2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells’ invasion
por: Zhang, Chao, et al.
Publicado: (2017)

Evaluation of Use of RPMI Medium to Preserve Cell Morphology for Pleural/Peritoneal Fluid Cytology
por: Rani, Usha, et al.
Publicado: (2022)

Overexpression of MMP13 in human osteoarthritic cartilage is associated with the SMAD-independent TGF-β signalling pathway
por: Aref-Eshghi, Erfan, et al.
Publicado: (2015)

Retraction Note: TGF-β2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells’ invasion
por: Zhang, Chao, et al.
Publicado: (2021)

SB225002 inhibits prostate cancer invasion and attenuates the expression of BSP, OPN and MMP-2
por: Xu, Meng, et al.
Publicado: (2018)

TGF-β1 facilitates MT1-MMP-mediated proMMP-9 activation and invasion in oral squamous cell carcinoma cells
por: Yamahana, Hirari, et al.
Publicado: (2021)

TGF-β-MTA1-SMAD7-SMAD3-SOX4-EZH2 Signaling Axis Promotes Viability, Migration, Invasion and EMT of Hepatocellular Carcinoma Cells
por: Zhang, Kangjun, et al.
Publicado: (2021)

MicroRNA-362 negatively and positively regulates SMAD4 expression in TGF-β/SMAD signaling to suppress cell migration and invasion
por: Cheng, Han Ping, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_dl2a1a2mcicscjp5bmjrp18so9