Apogossypolone induces apoptosis and autophagy in nasopharyngeal carcinoma cells in an in vitro and in vivo study

Nasopharyngeal carcinoma (NPC) has a high incidence and mortality rate, particularly in Southern China. Apogossypolone (ApoG2) is a novel derivative of gossypol with antitumor activity and less toxicity. The human NPC CNE-2 cell line was studied in the in vitro model; whilst 4 week-old male nude mic...

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Detalles Bibliográficos
Autores principales: Zheng, Ruinian, Chen, Kexu, Zhang, Yu, Huang, Jie, Shi, Fengrong, Wu, Gang, Wang, Senming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494797/
https://www.ncbi.nlm.nih.gov/pubmed/28693230
http://dx.doi.org/10.3892/ol.2017.6176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494797/
https://www.ncbi.nlm.nih.gov/pubmed/28693230
http://dx.doi.org/10.3892/ol.2017.6176

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