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Prediction of Escherichia coli expression performance in microtiter plates by analyzing only the temporal development of scattered light during culture
BACKGROUND: Escherichia coli is often used for recombinant protein production. The expression of recombinant proteins negatively affects the microbial growth, thus, a balance between protein expression and biomass formation is preferable to reach high product- and space-time-yield. Already in screen...
Autores principales: | Ladner, Tobias, Mühlmann, Martina, Schulte, Andreas, Wandrey, Georg, Büchs, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494857/ https://www.ncbi.nlm.nih.gov/pubmed/28680476 http://dx.doi.org/10.1186/s13036-017-0064-5 |
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