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Somatic loss of estrogen receptor beta and p53 synergize to induce breast tumorigenesis

BACKGROUND: Upregulation of estrogen receptor beta (ERβ) in breast cancer cells is associated with epithelial maintenance, decreased proliferation and invasion, and a reduction in the expression of the receptor has been observed in invasive breast tumors. However, proof of an association between los...

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Detalles Bibliográficos
Autores principales: Bado, Igor, Nikolos, Fotis, Rajapaksa, Gayani, Wu, Wanfu, Castaneda, Jessica, Krishnamurthy, Savitri, Webb, Paul, Gustafsson, Jan-Åke, Thomas, Christoforos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494907/
https://www.ncbi.nlm.nih.gov/pubmed/28673316
http://dx.doi.org/10.1186/s13058-017-0872-z