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Somatic loss of estrogen receptor beta and p53 synergize to induce breast tumorigenesis
BACKGROUND: Upregulation of estrogen receptor beta (ERβ) in breast cancer cells is associated with epithelial maintenance, decreased proliferation and invasion, and a reduction in the expression of the receptor has been observed in invasive breast tumors. However, proof of an association between los...
Autores principales: | Bado, Igor, Nikolos, Fotis, Rajapaksa, Gayani, Wu, Wanfu, Castaneda, Jessica, Krishnamurthy, Savitri, Webb, Paul, Gustafsson, Jan-Åke, Thomas, Christoforos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494907/ https://www.ncbi.nlm.nih.gov/pubmed/28673316 http://dx.doi.org/10.1186/s13058-017-0872-z |
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