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Clinical Response to Vedolizumab in Ulcerative Colitis Patients Is Associated with Changes in Integrin Expression Profiles

BACKGROUND: Despite large clinical success, deeper insights into the immunological effects of vedolizumab therapy for inflammatory bowel diseases are scarce. In particular, the reasons for differential clinical response in individual patients, the precise impact on the equilibrium of integrin-expres...

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Detalles Bibliográficos
Autores principales: Fuchs, Friederike, Schillinger, Daniela, Atreya, Raja, Hirschmann, Simon, Fischer, Sarah, Neufert, Clemens, Atreya, Imke, Neurath, Markus F., Zundler, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495081/
https://www.ncbi.nlm.nih.gov/pubmed/28717358
http://dx.doi.org/10.3389/fimmu.2017.00764