Cargando…

The Guanine-Nucleotide Exchange Factor Caldag Gefi Fine-Tunes Functional Properties of Regulatory T Cells

Using quantitative phosphopeptide sequencing of unstimulated versus stimulated primary murine Foxp3(+) regulatory and Foxp3(–) conventional T cells (Tregs and Tconv, respectively), we detected a novel and differentially regulated tyrosine phosphorylation site within the C1 domain of the guanine-nucl...

Descripción completa

Detalles Bibliográficos
Autores principales: Niemz, Jana, Kliche, Stefanie, Pils, Marina C., Morrison, Eliot, Manns, Annika, Freund, Christian, Crittenden, Jill R., Graybiel, Ann M., Galla, Melanie, Jänsch, Lothar, Huehn, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Akadémiai Kiadó 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495083/
https://www.ncbi.nlm.nih.gov/pubmed/28690878
http://dx.doi.org/10.1556/1886.2017.00007

Ejemplares similares