Cargando…
The Guanine-Nucleotide Exchange Factor Caldag Gefi Fine-Tunes Functional Properties of Regulatory T Cells
Using quantitative phosphopeptide sequencing of unstimulated versus stimulated primary murine Foxp3(+) regulatory and Foxp3(–) conventional T cells (Tregs and Tconv, respectively), we detected a novel and differentially regulated tyrosine phosphorylation site within the C1 domain of the guanine-nucl...
Autores principales: | Niemz, Jana, Kliche, Stefanie, Pils, Marina C., Morrison, Eliot, Manns, Annika, Freund, Christian, Crittenden, Jill R., Graybiel, Ann M., Galla, Melanie, Jänsch, Lothar, Huehn, Jochen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Akadémiai Kiadó
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495083/ https://www.ncbi.nlm.nih.gov/pubmed/28690878 http://dx.doi.org/10.1556/1886.2017.00007 |
Ejemplares similares
-
CalDAG-GEFI mediates striatal cholinergic modulation of dendritic excitability, synaptic plasticity and psychomotor behaviors
por: Crittenden, Jill R., et al.
Publicado: (2021) -
A LAD-III syndrome is associated with defective expression of the Rap-1 activator CalDAG-GEFI in lymphocytes, neutrophils, and platelets
por: Pasvolsky, Ronit, et al.
Publicado: (2007) -
Identification of a severe bleeding disorder in humans caused by a mutation in CalDAG-GEFI
por: Muller, William A.
Publicado: (2014) -
Human CalDAG-GEFI gene (RASGRP2) mutation affects platelet function and causes severe bleeding
por: Canault, Matthias, et al.
Publicado: (2014) -
Identification of two novel mutations in RASGRP2 affecting platelet CalDAG-GEFI expression and function in patients with bleeding diathesis
por: Sevivas, Teresa, et al.
Publicado: (2017)