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Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA

We recently identified pathogenic KIF1Bβ mutations in sympathetic nervous system malignancies that are defective in developmental apoptosis. Here we deleted KIF1Bβ in the mouse sympathetic nervous system and observed impaired sympathetic nervous function and misexpression of genes required for sympa...

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Detalles Bibliográficos
Autores principales:	Fell, Stuart M., Li, Shuijie, Wallis, Karin, Kock, Anna, Surova, Olga, Rraklli, Vilma, Höfig, Carolin S., Li, Wenyu, Mittag, Jens, Henriksson, Marie Arsenian, Kenchappa, Rajappa S., Holmberg, Johan, Kogner, Per, Schlisio, Susanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495120/ https://www.ncbi.nlm.nih.gov/pubmed/28637693 http://dx.doi.org/10.1101/gad.297077.117

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