Nosocomial Plasmodium falciparum infections confirmed by molecular typing in Medellín, Colombia

Three cases of nosocomial malaria are reported from patients of the Internal Medicine Ward of a tertiary University teaching hospital in Medellin, Colombia. Epidemiological research, based on entomological captures, medical records review and interviews of nursery staff about patient care practices...

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Detalles Bibliográficos
Autores principales: González, Lina, Ochoa, Jesus, Franco, Liliana, Arroyave, Marta, Restrepo, Eliana, Blair, Silvia, Maestre, Amanda
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549514/
https://www.ncbi.nlm.nih.gov/pubmed/15703072
http://dx.doi.org/10.1186/1475-2875-4-9
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author González, Lina
Ochoa, Jesus
Franco, Liliana
Arroyave, Marta
Restrepo, Eliana
Blair, Silvia
Maestre, Amanda
author_facet González, Lina
Ochoa, Jesus
Franco, Liliana
Arroyave, Marta
Restrepo, Eliana
Blair, Silvia
Maestre, Amanda
author_sort González, Lina
collection PubMed
description Three cases of nosocomial malaria are reported from patients of the Internal Medicine Ward of a tertiary University teaching hospital in Medellin, Colombia. Epidemiological research, based on entomological captures, medical records review and interviews of nursery staff about patient care practices potentially involving contact with blood, were carried out. Molecular characterization of Plasmodium falciparum was based on the amplification of MSP1, MSP2 and GLURP genes. This method enabled confirmation of the same P. falciparum genotype in all three patients as well as in a fourth one (index case). The presence of nosocomial malaria was confirmed and it was concluded that the most likely source of transmission was through multi-dose preparations of heparin applied to heparin locks.
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spelling pubmed-5495142005-02-25 Nosocomial Plasmodium falciparum infections confirmed by molecular typing in Medellín, Colombia González, Lina Ochoa, Jesus Franco, Liliana Arroyave, Marta Restrepo, Eliana Blair, Silvia Maestre, Amanda Malar J Case Report Three cases of nosocomial malaria are reported from patients of the Internal Medicine Ward of a tertiary University teaching hospital in Medellin, Colombia. Epidemiological research, based on entomological captures, medical records review and interviews of nursery staff about patient care practices potentially involving contact with blood, were carried out. Molecular characterization of Plasmodium falciparum was based on the amplification of MSP1, MSP2 and GLURP genes. This method enabled confirmation of the same P. falciparum genotype in all three patients as well as in a fourth one (index case). The presence of nosocomial malaria was confirmed and it was concluded that the most likely source of transmission was through multi-dose preparations of heparin applied to heparin locks. BioMed Central 2005-02-09 /pmc/articles/PMC549514/ /pubmed/15703072 http://dx.doi.org/10.1186/1475-2875-4-9 Text en Copyright © 2005 González et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
González, Lina
Ochoa, Jesus
Franco, Liliana
Arroyave, Marta
Restrepo, Eliana
Blair, Silvia
Maestre, Amanda
Nosocomial Plasmodium falciparum infections confirmed by molecular typing in Medellín, Colombia
title Nosocomial Plasmodium falciparum infections confirmed by molecular typing in Medellín, Colombia
title_full Nosocomial Plasmodium falciparum infections confirmed by molecular typing in Medellín, Colombia
title_fullStr Nosocomial Plasmodium falciparum infections confirmed by molecular typing in Medellín, Colombia
title_full_unstemmed Nosocomial Plasmodium falciparum infections confirmed by molecular typing in Medellín, Colombia
title_short Nosocomial Plasmodium falciparum infections confirmed by molecular typing in Medellín, Colombia
title_sort nosocomial plasmodium falciparum infections confirmed by molecular typing in medellín, colombia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549514/
https://www.ncbi.nlm.nih.gov/pubmed/15703072
http://dx.doi.org/10.1186/1475-2875-4-9
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