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Simultaneous inhibition of aryl hydrocarbon receptor (AhR) and Src abolishes androgen receptor signaling
Altered c-Src activity has been strongly implicated in the development, growth, progression, and metastasis of human cancers including prostate cancer. Src is known to regulate several biological functions of tumor cells, including proliferation. There are several Src inhibitors under evaluation for...
Autores principales: | Ghotbaddini, Maryam, Cisse, Keyana, Carey, Alexis, Powell, Joann B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495210/ https://www.ncbi.nlm.nih.gov/pubmed/28671964 http://dx.doi.org/10.1371/journal.pone.0179844 |
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