T cell activation and differentiation is modulated by a CD6 domain 1 antibody Itolizumab

CD6 is associated with T-cell modulation and is implicated in several autoimmune diseases. We previously demonstrated that Itolizumab, a CD6 domain 1 (CD6D1) specific humanized monoclonal antibody, inhibited the proliferation and cytokine production by T lymphocytes stimulated with anti-CD3 antibody...

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Detalles Bibliográficos
Autores principales: Bughani, Usha, Saha, Arindam, Kuriakose, Anshu, Nair, Reshmi, Sadashivarao, Ravindra B., Venkataraman, Rasika, Patel, Swati, Deshchougule, Anuja Tushar, S., Satish Kumar, Montero, Enrique, Pai, Harish V., Palanivelu, Dinesh V., Melarkode, Ramakrishnan, Nair, Pradip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495335/
https://www.ncbi.nlm.nih.gov/pubmed/28672038
http://dx.doi.org/10.1371/journal.pone.0180088

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