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Photoreceptor oxidative stress in hyperoxia-induced proliferative retinopathy accelerates rd8 degeneration

To investigate the impact of photoreceptor oxidative stress on photoreceptor degeneration in mice carrying the rd8 mutation (C57BL/6N). We compared the hyperoxia-induced proliferative retinopathy (HIPR) model in two mouse strains (C57BL/6J and C57BL/6N). Pups were exposed to 75% oxygen, starting at...

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Detalles Bibliográficos
Autores principales: Lajko, Michelle, Cardona, Herminio J., Taylor, Joann M., Farrow, Kathryn N., Fawzi, Amani A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495396/
https://www.ncbi.nlm.nih.gov/pubmed/28671996
http://dx.doi.org/10.1371/journal.pone.0180384

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