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Interleukin-6 regulates iron-related proteins through c-Jun N-terminal kinase activation in BV2 microglial cell lines

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by the loss of dopaminergic (DA) neurons in the substantia nigra (SN) and subsequent DA depletion in the striatum. Microglia activation and nigral iron accumulation play important roles in the pathogenesis of PD. Activated...

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Detalles Bibliográficos
Autores principales: Zhou, Shida, Du, Xinxing, Xie, Junxia, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495437/
https://www.ncbi.nlm.nih.gov/pubmed/28672025
http://dx.doi.org/10.1371/journal.pone.0180464

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