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Functional complementation of RNA interference mutants in trypanosomes

BACKGROUND: In many eukaryotic cells, double-stranded RNA (dsRNA) triggers RNA interference (RNAi), the specific degradation of RNA of homologous sequence. RNAi is now a major tool for reverse-genetics projects, including large-scale high-throughput screens. Recent reports have questioned the specif...

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Detalles Bibliográficos
Autores principales:	Rusconi, Filippo, Durand-Dubief, Mickaël, Bastin, Philippe
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549545/ https://www.ncbi.nlm.nih.gov/pubmed/15703078 http://dx.doi.org/10.1186/1472-6750-5-6

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