Cargando…
Molecular interaction between type 2 diabetes and Alzheimer’s disease through cross-seeding of protein misfolding
Numerous epidemiological studies have shown a significantly higher risk for development of Alzheimer’s disease (AD) in patients affected by type 2 diabetes (T2D), but the molecular mechanism responsible for this association is presently unknown. Both diseases are considered protein misfolding disord...
Autores principales: | Moreno-Gonzalez, Ines, Edwards, George, Salvadores, Natalia, Shahnawaz, Mohammad, Diaz-Espinoza, Rodrigo, Soto, Claudio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495631/ https://www.ncbi.nlm.nih.gov/pubmed/28044060 http://dx.doi.org/10.1038/mp.2016.230 |
Ejemplares similares
-
Cross-Seeding of Misfolded Proteins: Implications for Etiology and Pathogenesis of Protein Misfolding Diseases
por: Morales, Rodrigo, et al.
Publicado: (2013) -
Transmission of cerebral amyloid pathology by peripheral administration of misfolded Aβ aggregates.
por: Morales, Rodrigo, et al.
Publicado: (2021) -
Kosmotropic Anions Promote Conversion of Recombinant Prion Protein into a PrP(Sc)-Like Misfolded Form
por: Diaz-Espinoza, Rodrigo, et al.
Publicado: (2012) -
Strain-dependent profile of misfolded prion protein aggregates
por: Morales, Rodrigo, et al.
Publicado: (2016) -
Role of Protein Misfolding and Proteostasis Deficiency in Protein Misfolding Diseases and Aging
por: Cuanalo-Contreras, Karina, et al.
Publicado: (2013)