In silico identification and in vivo validation of miR-495 as a novel regulator of motivation for cocaine that targets multiple addiction-related networks in the nucleus accumbens

MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression and are implicated in the etiology of several neuropsychiatric disorders, including substance use disorders (SUDs). Using in silico genome-wide sequence analyses, we identified miR-495 as a miRNA whose predicted targ...

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Detalles Bibliográficos
Autores principales: Bastle, R M, Oliver, R J, Gardiner, A S, Pentkowski, N S, Bolognani, F, Allan, A M, Chaudhury, T, St. Peter, M, Galles, N, Smith, C, Neisewander, J L, Perrone-Bizzozero, N I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495632/
https://www.ncbi.nlm.nih.gov/pubmed/28044061
http://dx.doi.org/10.1038/mp.2016.238

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