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Endotoxin tolerance in mast cells, its consequences for IgE-mediated signalling, and the effects of BCL3 deficiency

Stimulation with lipopolysaccharide (LPS; endotoxin) not only causes rapid production of proinflammatory cytokines, but also induces a state of LPS hypo-responsiveness to a second LPS stimulation (endotoxin tolerance (ET)). Murine bone marrow-derived MCs (BMMCs) and peritoneal MCs (PMCs) developed E...

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Detalles Bibliográficos
Autores principales:	Poplutz, Magdalena, Levikova, Maryna, Lüscher-Firzlaff, Juliane, Lesina, Marina, Algül, Hana, Lüscher, Bernhard, Huber, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495797/ https://www.ncbi.nlm.nih.gov/pubmed/28674400 http://dx.doi.org/10.1038/s41598-017-04890-4

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