Increased methylation and decreased expression of homeobox genes TLX1, HOXA10 and DLX5 in human placenta are associated with trophoblast differentiation

Homeobox genes regulate embryonic and placental development, and are widely expressed in the human placenta, but their regulatory control by DNA methylation is unclear. DNA methylation analysis was performed on human placentae from first, second and third trimesters to determine methylation patterns...

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Detalles Bibliográficos
Autores principales: Novakovic, Boris, Fournier, Thierry, Harris, Lynda K., James, Joanna, Roberts, Claire T., Yong, Hannah E. J., Kalionis, Bill, Evain-Brion, Danièle, Ebeling, Peter R., Wallace, Euan M., Saffery, Richard, Murthi, Padma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495813/
https://www.ncbi.nlm.nih.gov/pubmed/28674422
http://dx.doi.org/10.1038/s41598-017-04776-5

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