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Multiple Metabolic Hits Converge on CD36 as Novel Mediator of Tubular Epithelial Apoptosis in Diabetic Nephropathy

BACKGROUND: Diabetic nephropathy (DNP) is a common complication of type 1 and type 2 diabetes mellitus and the most common cause of kidney failure. While DNP manifests with albuminuria and diabetic glomerulopathy, its progression correlates best with tubular epithelial degeneration (TED) and interst...

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Detalles Bibliográficos
Autores principales: Susztak, Katalin, Ciccone, Emilio, McCue, Peter, Sharma, Kumar, Böttinger, Erwin P
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549593/
https://www.ncbi.nlm.nih.gov/pubmed/15737001
http://dx.doi.org/10.1371/journal.pmed.0020045