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EGFR Inhibition in Non-Small Cell Lung Cancer: Resistance, Once Again, Rears Its Ugly Head
Most patients with non-small cell lung cancer who initially respond to gefitinib or erlotinib (tyrosine kinase inhibitors) ultimately develop resistance and disease relapse. What is the mechanism for this resistance?
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549608/ https://www.ncbi.nlm.nih.gov/pubmed/15736989 http://dx.doi.org/10.1371/journal.pmed.0020075 |