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Treatment of Nonclassic 11-Hydroxylase Deficiency with Ashwagandha Root

An elderly woman presented with acne and male pattern alopecia, which upon diagnostic evaluation was found to be due to nonclassic 11-hydroxylase deficiency. We previously reported that Ashwagandha root ameliorates nonclassic 3-β-ol dehydrogenase and aldosterone synthase deficiencies. This is the fi...

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Autores principales: Powell, Daniel, Inoue, Taiga, Bahtiyar, Gül, Fenteany, Gabriel, Sacerdote, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496100/
https://www.ncbi.nlm.nih.gov/pubmed/28713602
http://dx.doi.org/10.1155/2017/1869560
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author Powell, Daniel
Inoue, Taiga
Bahtiyar, Gül
Fenteany, Gabriel
Sacerdote, Alan
author_facet Powell, Daniel
Inoue, Taiga
Bahtiyar, Gül
Fenteany, Gabriel
Sacerdote, Alan
author_sort Powell, Daniel
collection PubMed
description An elderly woman presented with acne and male pattern alopecia, which upon diagnostic evaluation was found to be due to nonclassic 11-hydroxylase deficiency. We previously reported that Ashwagandha root ameliorates nonclassic 3-β-ol dehydrogenase and aldosterone synthase deficiencies. This is the first report of its use being associated with amelioration of nonclassic 11-hydroxylase deficiency, where its apparent effects appear to be dose-related.
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spelling pubmed-54961002017-07-16 Treatment of Nonclassic 11-Hydroxylase Deficiency with Ashwagandha Root Powell, Daniel Inoue, Taiga Bahtiyar, Gül Fenteany, Gabriel Sacerdote, Alan Case Rep Endocrinol Case Report An elderly woman presented with acne and male pattern alopecia, which upon diagnostic evaluation was found to be due to nonclassic 11-hydroxylase deficiency. We previously reported that Ashwagandha root ameliorates nonclassic 3-β-ol dehydrogenase and aldosterone synthase deficiencies. This is the first report of its use being associated with amelioration of nonclassic 11-hydroxylase deficiency, where its apparent effects appear to be dose-related. Hindawi 2017 2017-06-20 /pmc/articles/PMC5496100/ /pubmed/28713602 http://dx.doi.org/10.1155/2017/1869560 Text en Copyright © 2017 Daniel Powell et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Powell, Daniel
Inoue, Taiga
Bahtiyar, Gül
Fenteany, Gabriel
Sacerdote, Alan
Treatment of Nonclassic 11-Hydroxylase Deficiency with Ashwagandha Root
title Treatment of Nonclassic 11-Hydroxylase Deficiency with Ashwagandha Root
title_full Treatment of Nonclassic 11-Hydroxylase Deficiency with Ashwagandha Root
title_fullStr Treatment of Nonclassic 11-Hydroxylase Deficiency with Ashwagandha Root
title_full_unstemmed Treatment of Nonclassic 11-Hydroxylase Deficiency with Ashwagandha Root
title_short Treatment of Nonclassic 11-Hydroxylase Deficiency with Ashwagandha Root
title_sort treatment of nonclassic 11-hydroxylase deficiency with ashwagandha root
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496100/
https://www.ncbi.nlm.nih.gov/pubmed/28713602
http://dx.doi.org/10.1155/2017/1869560
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