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Significantly enhanced lung metastasis and reduced organ NK cell functions in diet-induced obese rats
BACKGROUND: Obesity was identified as a major risk factor for malignant diseases, but underlying mechanisms remain unclear. Natural killer (NK) cells, a pivotal aspect of innate immunity, are capable of identifying and killing virally infected and tumor cells. Previous studies have shown altered NK...
Autores principales: | Spielmann, J., Hanke, J., Knauf, D., Ben-Eliyahu, S., Jacobs, R., Stangl, G. I., Bähr, I., Kielstein, H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496225/ https://www.ncbi.nlm.nih.gov/pubmed/28690853 http://dx.doi.org/10.1186/s40608-017-0161-5 |
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