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UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression

BACKGROUND: Uridine 5′-diphosphate-glucuronosyltransferase 2B (UGT2B) genes code for enzymes that catalyze the clearance of testosterone, dihydrotestosterone (DHT), and DHT metabolites in the prostate basal and luminal tissue. The expression of the UGT2B15, UGT2B17, and UGT2B28 enzymes has not been...

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Detalles Bibliográficos
Autores principales: Grant, Delores J., Chen, Zinan, Howard, Lauren E., Wiggins, Emily, De Hoedt, Amanda, Vidal, Adriana C., Carney, Skyla T., Squires, Jill, Magyar, Clara E., Huang, Jiaoti, Freedland, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496250/
https://www.ncbi.nlm.nih.gov/pubmed/28673330
http://dx.doi.org/10.1186/s12885-017-3463-6