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Induction of apoptosis and proliferation inhibition of hepatocellular carcinoma by 6-chloro-2-methoxy-N-(phenylmethyl)-9-acridinamine (BA): in vitro and vivo studies

BACKGROUND: 6-Chloro-2-methoxy-N-(phenylmethyl)-9-acridinamine (BA), a novel sponge-derived compound, has been reported to elicit a cytotoxic effect by inhibiting cell proliferation. METHODS: In this study, we investigated the anti-tumor effect of BA in human hepatocellular carcinoma (HCC) in vitro...

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Detalles Bibliográficos
Autores principales: Huang, Yun, Liu, Guohua, Yang, Feng, Xing, Xiaowei, Li, Ying, Huang, Zhijun, Yuan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496258/
https://www.ncbi.nlm.nih.gov/pubmed/28680363
http://dx.doi.org/10.1186/s12935-017-0435-5