Abnormal circadian oscillation of hippocampal MAPK activity and power spectrums in NF1 mutant mice

Studies have implied that the circadian oscillation of mitogen-activated protein kinase (MAPK) signal pathways is crucial for hippocampus-dependent memory. NF1 mouse models (Nf1 heterozygous null mutants; Nf1 (+/−)) displayed enhanced MAPK activity in the hippocampus and resulted in memory deficits....

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Detalles Bibliográficos
Autores principales: Chen, Lei, Serdyuk, Tatiana, Yang, Beimeng, Wang, Shuai, Chen, Shiqing, Chu, Xixia, Zhang, Xu, Song, Jinjing, Bao, Hechen, Zhou, Chengbin, Wang, Xiang, Dong, Shuangle, Song, Lulu, Chen, Fujun, He, Guang, He, Lin, Zhou, Ying, Li, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496334/
https://www.ncbi.nlm.nih.gov/pubmed/28673309
http://dx.doi.org/10.1186/s13041-017-0309-8

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