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Effect of pharmacogenetics on plasma lumefantrine pharmacokinetics and malaria treatment outcome in pregnant women

BACKGROUND: Pregnancy has considerable effects on the pharmacokinetic properties of drugs used to treat uncomplicated Plasmodium falciparum malaria. The role of pharmacogenetic variation on anti-malarial drug disposition and efficacy during pregnancy is not well investigated. The study aimed to exam...

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Detalles Bibliográficos
Autores principales:	Mutagonda, Ritah F., Kamuhabwa, Appolinary A. R., Minzi, Omary M. S., Massawe, Siriel N., Asghar, Muhammad, Homann, Manijeh V., Färnert, Anna, Aklillu, Eleni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496343/ https://www.ncbi.nlm.nih.gov/pubmed/28673292 http://dx.doi.org/10.1186/s12936-017-1914-9

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