Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer

Cancers are metabolic entities wherein cancer cells adapt their metabolism to their oncogenic agenda and microenvironmental influences. Metabolically different cancer cell subpopulations collaborate to optimize nutrient delivery with respect to immediate bioenergetic and biosynthetic needs. They can...

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Detalles Bibliográficos
Autores principales: Baldini, Nicola, De Milito, Angelo, Feron, Olivier, Gillies, Robert J., Michiels, Carine, Otto, Angela M., Pastoreková, Silvia, Pedersen, Stine F., Porporato, Paolo E., Sonveaux, Pierre, Supuran, Claudiu T., Avnet, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496414/
https://www.ncbi.nlm.nih.gov/pubmed/28725193
http://dx.doi.org/10.3389/fphar.2017.00411
Descripción
Sumario:Cancers are metabolic entities wherein cancer cells adapt their metabolism to their oncogenic agenda and microenvironmental influences. Metabolically different cancer cell subpopulations collaborate to optimize nutrient delivery with respect to immediate bioenergetic and biosynthetic needs. They can also metabolically exploit host cells. These metabolic networks are directly linked with cancer progression, treatment resistance and relapse. Conversely, metabolic alterations in cancer are exploited for anticancer therapy, imaging and personalized medicine. These topics were addressed at the 3rd annual meeting of the International Society of Cancer Metabolism (ISCaM) in Brussels, Belgium, on 26–29 October 2016.

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