Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?

Phenotypic plasticity, the ability of cells to reversibly alter their phenotypes in response to signals, presents a significant clinical challenge to treating solid tumors. Tumor cells utilize phenotypic plasticity to evade therapies, metastasize, and colonize distant organs. As a result, phenotypic...

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Detalles Bibliográficos
Autores principales: Jolly, Mohit Kumar, Tripathi, Satyendra C., Somarelli, Jason A., Hanash, Samir M., Levine, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496493/
https://www.ncbi.nlm.nih.gov/pubmed/28548388
http://dx.doi.org/10.1002/1878-0261.12084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496493/
https://www.ncbi.nlm.nih.gov/pubmed/28548388
http://dx.doi.org/10.1002/1878-0261.12084

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